Pregnant Rat Moms Need their Sleep

“maternal sleep deprivation at different stages of pregnancy leads to a significant increase in depression and anxiety, and dramatic deficits in spatial learning and memory.”

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Gene Variant for Narcolepsy with Cataplexy is Identified

Study published in Sleep journal found subject with a particular DQB1 variant had 251X higher risk for narcolepsy with cataplexy. DQB1 Locus Alone Explains Most of the Risk and Protection in Narcolepsy with Cataplexy in Europe Study Objective: Prior research has identified five common genetic variants associated with narcolepsy with cataplexy in Caucasian patients. To…

Night Shift Workers Double Their Risk of Breast Cancer

In earlier posts on sleep [1, 2, 3] we’ve seen how disturbances to circadian rhythm can result in alterations to cell-cycle and function. This Norwegian study finds that long-term night shift can double the risk of breast cancer. OPEN ACCESS See also a 2001 paper Light at Night, Shiftwork, and Breast Cancer Risk Analysis of polymorphisms…

How Food Resets Your Circadian Clock

Recall the previous post on how disturbing circadian cycles results in disturbances to insulin response and promotes fat deposition. These findings indicate that because circadian clock is sensitive to nutrient pathways, eating resets your clock to what is normally its ‘active’ state. And that’s why you shouldn’t eat at night. http://www.sciencedirect.com/science/article/pii/S1550413113000077 O-GlcNAc Signaling Entrains the…