C.difficile move in when Bacteroides, Lachnospiraceae, and Ruminococcaceae move out

It’s hard to move into a house that is already occupied. Clostridium difficile infections are a little like that; this study found absence of certain types of bacteria is associated with colonization. Microbiome Data Distinguish Patients with Clostridium difficile Infection and Non-C. difficile-Associated Diarrhea from Healthy Controls The gut microbiome, composed of the trillions of…

Poop-freezies to treat Clostridium difficile Infection

The use of frozen fecal samples for the treatment of C.difficile infection showed a high success rate in this study. Up or down – nasogastric or colonoscopy inoculation – both were effective., 70% after single treatment which went up to 90% on re-treatment. See also last year’s “The Enemy of My Enemy” Goes Microbial  …

C. difficile spores stick to hands of healthcare workers

A quarter of health-care workers’s hands are contaminated with C.difficile spore contamination after caring for C.dificile infected patients. The lesson here is that health-care workers should use protective gloves and fresh gloves with every patient.  Of course, glove use is not a substitute for proper hygiene – that means proper washing with soap and water…

Babies wage biological warfare on adults.

Infants can be colonized by toxin producing strains of Clostridium difficile but rarely develop disease. Infants and children could play a source in the spread of C. difficile disease to adults. http://jcm.asm.org/content/early/2013/10/24/JCM.01701-13.abstract http://www.asm.org/images/Communications/tips/2013/1113cdifficile.pdf Toxin-producing Clostridium difficile strains as long-term gut colonizers of healthy infants Clostridium difficile is a colonizer of the human gut, and toxin-producing…