Human urine interferes with pili and inhibits E.coli attachment to bladder. Human Urine Decreases Function and Expression of Type 1 Pili in Uropathogenic Escherichia coli IMPORTANCE Urinary tract infections (UTIs) are extremely common infections, frequently caused by uropathogenic Escherichia coli (UPEC), that are treated with antibiotics but often recur. Therefore, UTI treatment both is complicated by…