Job Stress Raises LDL Cholesterol

People with job stress are more likely to have abnormally high LDL and triglycerides and lower “good” HDL cholesterol.

http://sjp.sagepub.com/content/41/2/142.abstract

The relationship between job stress and dyslipidemia

Aims: To investigate whether there is an association between job stress, lipid profile and dyslipidemia diagnosis.

Methods: This study used a questionnaire to evaluate job stress and lifestyle variables in 91,593 workers undergoing periodic checkups. Serum lipid levels were measured in all cases. Results: The prevalence of job stress was 8.7% (95% CI, 8.5–8.8%). In bivariate analyses, job stress was significantly associated with previous dyslipidemia diagnosis (p < 0.001), lipid-lowering therapy (p < 0.001), and altered total-cholesterol (p = 0.001), HDL-cholesterol (p < 0.001) and LDL-cholesterol levels (p = 0.025). After adjusting for potential confounding variables, job stress was still associated with current dyslipidemia diagnosis (OR = 1.10; 95% CI, 1.04–1.17), high LDL-cholesterol (OR = 1.14; 95% CI, 1.05–1.23), low HDL-cholesterol (OR 1.08; 95% CI, 1.01–1.15), high total cholesterol/HDL-cholesterol ratio (OR 1.13; 95% CI, 1.05–1.23) and high LDL-cholesterol/HDL-cholesterol ratio (OR 1.11; 95% CI, 1.04–1.19).

Conclusion: These results support the hypothesis of an association between job stress and lipid disturbances.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s