Wrapping Beta-cells in sugar-derivative makes them implantable

This is a really neat approach. Encapsulating beta cells (insulin producing cells) an alginate derivative makes them implantable without eliciting an immune response and normalizes glucose in mice.   Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice The transplantation of glucose-responsive, insulin-producing cells offers the potential for restoring glycemic control…

Nutrition & Metabolism 2015 12:59

DOI: 10.1186/s12986-015-0055-9

Muscle Adaptations with Endurance and Resistance Training

Good overview and some information that might result in a change in exercise regimen. Nutrition & Metabolism 2015 12:59 DOI: 10.1186/s12986-015-0055-9 Glycogen availability and skeletal muscle adaptations with endurance and resistance exercise It is well established that glycogen depletion affects endurance exercise performance negatively. Moreover, numerous studies have demonstrated that post-exercise carbohydrate ingestion improves exercise recovery by…

Dietary Eicosapentaenoic acid restores Mitochondria in Old Mice

It might be too soon to start popping Eicosapentaenoic acid supplements to boost aging muscles; still the findings are intriguing. Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice Mitochondrial dysfunction is often observed in aging skeletal muscle and is implicated in age-related declines in physical function. Early evidence…

Skin microbiome influences outcome of infection

  The make up of the bacterial community on the skin influences whether subjects developed pustules after intentional inoculation or whether the infection resolved itself. These results suggest that at baseline, resolvers and pustule formers have distinct skin bacterial communities which change in response to infection and the resultant immune response. OPEN ACCESS paper The…

Gamble in Your Second Language – mitigating ‘hot hand’ fallacy

Another good reason to learn a 2nd language.   Full paper. Second Language Feedback Abolishes the “Hot Hand” Effect during Even-Probability Gambling Research into language–emotion interactions has revealed intriguing cognitive inhibition effects by emotionally negative words in bilinguals. Here, we turn to the domain of human risk taking and show that the experience of positive…

Trust is Lower Among Parkinson’s Disease Patients

Interesting findings in the differences between levels of trust between PD patients and control group. Trust behavior in Parkinson’s disease: results of a trust game experiment Background Parkinson’s Disease (PD) is a neurodegenerative disease characterized by motor symptoms, but in which behavioral and cognitive disturbances are also common. Trust, due to its pervasiveness in society,…

Melamine contamination in Nutritional Supplements

Study tested popular supplements available in South Africa – both produced and imported – and found almost half of the products positive for melamine.   Melamine contamination in nutritional supplements – Is it an alarm bell for the general consumer, athletes, and ‘Weekend Warriors’? Background Nutritional supplements are used or experimented with by consumers, notably…

The R.O.U.S. evolved in an island

We may have solved the origin of Princess Bride’s rodent of unusual size. Mainland size variation informs predictive models of exceptional insular body size change in rodents. The tendency for island populations of mammalian taxa to diverge in body size from their mainland counterparts consistently in particular directions is both impressive for its regularity and,…

Urinary Tract Infection: Pee Perturbs Pili Production

Human urine interferes with pili and inhibits E.coli attachment to bladder. Human Urine Decreases Function and Expression of Type 1 Pili in Uropathogenic Escherichia coli IMPORTANCE Urinary tract infections (UTIs) are extremely common infections, frequently caused by uropathogenic Escherichia coli (UPEC), that are treated with antibiotics but often recur. Therefore, UTI treatment both is complicated by…