Go Nuts!

Daily consumption of a handful of nuts (28g) is associated with reduced risk of cancer, diabetes and cardiovascular disease.   Nut consumption and risk of cardiovascular disease, total cancer, all-cause and cause-specific mortality: a systematic review and dose-response meta-analysis of prospective studies   Background Although nut consumption has been associated with a reduced risk of…

mtDNA deletions and age-related muscle loss

    Latent mitochondrial DNA deletion mutations drive muscle fiber loss at old age With age, somatically derived mitochondrial DNA (mtDNA) deletion mutations arise in many tissues and species. In skeletal muscle, deletion mutations clonally accumulate along the length of individual fibers. At high intrafiber abundances, these mutations disrupt individual cell respiration and are linked…

Wrapping Beta-cells in sugar-derivative makes them implantable

This is a really neat approach. Encapsulating beta cells (insulin producing cells) an alginate derivative makes them implantable without eliciting an immune response and normalizes glucose in mice.   Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice The transplantation of glucose-responsive, insulin-producing cells offers the potential for restoring glycemic control…

Nutrition & Metabolism 2015 12:59

DOI: 10.1186/s12986-015-0055-9

Muscle Adaptations with Endurance and Resistance Training

Good overview and some information that might result in a change in exercise regimen. Nutrition & Metabolism 2015 12:59 DOI: 10.1186/s12986-015-0055-9 Glycogen availability and skeletal muscle adaptations with endurance and resistance exercise It is well established that glycogen depletion affects endurance exercise performance negatively. Moreover, numerous studies have demonstrated that post-exercise carbohydrate ingestion improves exercise recovery by…

Dietary Eicosapentaenoic acid restores Mitochondria in Old Mice

It might be too soon to start popping Eicosapentaenoic acid supplements to boost aging muscles; still the findings are intriguing. Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice Mitochondrial dysfunction is often observed in aging skeletal muscle and is implicated in age-related declines in physical function. Early evidence…

Skin microbiome influences outcome of infection

  The make up of the bacterial community on the skin influences whether subjects developed pustules after intentional inoculation or whether the infection resolved itself. These results suggest that at baseline, resolvers and pustule formers have distinct skin bacterial communities which change in response to infection and the resultant immune response. OPEN ACCESS paper The…

Gamble in Your Second Language – mitigating ‘hot hand’ fallacy

Another good reason to learn a 2nd language.   Full paper. Second Language Feedback Abolishes the “Hot Hand” Effect during Even-Probability Gambling Research into language–emotion interactions has revealed intriguing cognitive inhibition effects by emotionally negative words in bilinguals. Here, we turn to the domain of human risk taking and show that the experience of positive…

Trust is Lower Among Parkinson’s Disease Patients

Interesting findings in the differences between levels of trust between PD patients and control group. Trust behavior in Parkinson’s disease: results of a trust game experiment Background Parkinson’s Disease (PD) is a neurodegenerative disease characterized by motor symptoms, but in which behavioral and cognitive disturbances are also common. Trust, due to its pervasiveness in society,…